SPE phase for solid phase extraction
The enrichment of hydrophilic analytes from polar matrices is a challenge because they often cannot be retained by C18 / C8-modified silica or hydrophobic polymer adsorbents. To overcome this issue MACHEREY-NAGEL developed CHROMABOND HLB, a hydrophilic-lipophilic balanced N-vinylpyrrolidone-divinylbenzene copolymer. Its lipophilic backbone interacts with nonpolar hydrocarbon residues of the analytes while the linked hydrophilic groups interact with polar functional groups to provide enhanced retention.
Download Flyer: CHROMABOND HLB
Advantages of CHROMABOND HLB
- Applicable for a wide range of analyte polarities
- Enhanced retention for polar compounds
- High loadability and outstanding performance
- Water wettable – even if bed runs dry, SPE can be continued
- The alternative to Oasis* HLB
Product portfolio: CHROMABOND HLB
* Oasis is a registered trademark of Waters Corporation, USA. The MACHEREY-NAGEL products are neither endorsed, nor sponsored by or affiliated with the Waters Corporation.
